prostate cancer tumor model balb Search Results


lncap  (Coriell Institute for Medical Research)
90
Coriell Institute for Medical Research lncap
Lncap, supplied by Coriell Institute for Medical Research, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gene involved in breast and prostate cancer  (PR Newswire Association LLC)
90
PR Newswire Association LLC gene involved in breast and prostate cancer
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Gene Involved In Breast And Prostate Cancer, supplied by PR Newswire Association LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1g4 tcr  (GenScript corporation)
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GenScript corporation 1g4 tcr
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rat androgenindependent prostate cancer cell line at-3 cells  (Johns Hopkins HealthCare)
90
Johns Hopkins HealthCare rat androgenindependent prostate cancer cell line at-3 cells
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softmax (2)  (SoftMax Inc)
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SoftMax Inc softmax (2)
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prostate cancer research  (MATHESON)
90
MATHESON prostate cancer research
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prostate cancer  (CureVac Inc)
90
CureVac Inc prostate cancer
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hereditary prostate cancer families  (Johns Hopkins HealthCare)
90
Johns Hopkins HealthCare hereditary prostate cancer families
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8-pcpt-2-o-me-camp  (BIOLOG Life Science Institute)
90
BIOLOG Life Science Institute 8-pcpt-2-o-me-camp
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8-pcpt-2′-o-me-camp  (Enzo Biochem)
90
Enzo Biochem 8-pcpt-2′-o-me-camp
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pcpt  (Santa Cruz Biotechnology)
90
Santa Cruz Biotechnology pcpt
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prostate cancer cell lines lncap  (ATCC)
99
ATCC prostate cancer cell lines lncap
(a) A heatmap showing expression of 37 significantly upregulated genes in cancer liquid biopsies. (b,c) Among 37 upregulated genes, 13 genes ( FH, SMARCB1, GRHPR, PHB, NACA, RPS11, RPL22, NPM1, EPCAM, TFG, HDAC6, ELK4, BRD3 ) were significantly upregulated in primary tumors (n=497) compared to normal (n=52) in TCGA data. In the heatmap, black dots next to the gene name mark the genes upregulated in primary tumor compare to normal in TCGA data. The TCGA project for PCa data is publicly available for download at https://portal.gdc.cancer.gov/projects/TCGA-PRAD . (d) These 13 genes were also tested in <t>two</t> <t>prostate</t> cancer cell lines <t>(LNCaP</t> and PC3), and most were overexpressed apart from NACA , which was downregulated in both cell lines; BRD3 and EPCAM , which were decreased in PC3 cells, and HDAC6 , which was downregulated in LNCaP cells. (e) Normalized Enrichment Score plot of the top 13 pathways in cancer urine. (f) Geneset Enrichment Score Plot (GSEA) of the TCA cycle (NES = 2.8, p-value = 0.0). (g) GSEA of the alanine, aspartate, and glutamate metabolism (NES = 2.42, p-value = 0.0). GSEA was conducted using GSEA software from the Broad Institute ( http://software.broadinstitute.org/gsea/index.jsp ).
Prostate Cancer Cell Lines Lncap, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Examples of News Stories on Human Genome Discoveries Relevant to Common Chronic Diseases <xref ref-type= a " width="100%" height="100%">

Journal: Preventing Chronic Disease

Article Title: Genomics and the Prevention and Control of Common Chronic Diseases: Emerging Priorities for Public Health Action

doi:

Figure Lengend Snippet: Examples of News Stories on Human Genome Discoveries Relevant to Common Chronic Diseases a

Article Snippet: Important discovery of gene involved in breast and prostate cancer , PR Newswire , Dec 15, 2004.

Techniques: Mutagenesis

(a) A heatmap showing expression of 37 significantly upregulated genes in cancer liquid biopsies. (b,c) Among 37 upregulated genes, 13 genes ( FH, SMARCB1, GRHPR, PHB, NACA, RPS11, RPL22, NPM1, EPCAM, TFG, HDAC6, ELK4, BRD3 ) were significantly upregulated in primary tumors (n=497) compared to normal (n=52) in TCGA data. In the heatmap, black dots next to the gene name mark the genes upregulated in primary tumor compare to normal in TCGA data. The TCGA project for PCa data is publicly available for download at https://portal.gdc.cancer.gov/projects/TCGA-PRAD . (d) These 13 genes were also tested in two prostate cancer cell lines (LNCaP and PC3), and most were overexpressed apart from NACA , which was downregulated in both cell lines; BRD3 and EPCAM , which were decreased in PC3 cells, and HDAC6 , which was downregulated in LNCaP cells. (e) Normalized Enrichment Score plot of the top 13 pathways in cancer urine. (f) Geneset Enrichment Score Plot (GSEA) of the TCA cycle (NES = 2.8, p-value = 0.0). (g) GSEA of the alanine, aspartate, and glutamate metabolism (NES = 2.42, p-value = 0.0). GSEA was conducted using GSEA software from the Broad Institute ( http://software.broadinstitute.org/gsea/index.jsp ).

Journal: bioRxiv

Article Title: Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery

doi: 10.1101/599514

Figure Lengend Snippet: (a) A heatmap showing expression of 37 significantly upregulated genes in cancer liquid biopsies. (b,c) Among 37 upregulated genes, 13 genes ( FH, SMARCB1, GRHPR, PHB, NACA, RPS11, RPL22, NPM1, EPCAM, TFG, HDAC6, ELK4, BRD3 ) were significantly upregulated in primary tumors (n=497) compared to normal (n=52) in TCGA data. In the heatmap, black dots next to the gene name mark the genes upregulated in primary tumor compare to normal in TCGA data. The TCGA project for PCa data is publicly available for download at https://portal.gdc.cancer.gov/projects/TCGA-PRAD . (d) These 13 genes were also tested in two prostate cancer cell lines (LNCaP and PC3), and most were overexpressed apart from NACA , which was downregulated in both cell lines; BRD3 and EPCAM , which were decreased in PC3 cells, and HDAC6 , which was downregulated in LNCaP cells. (e) Normalized Enrichment Score plot of the top 13 pathways in cancer urine. (f) Geneset Enrichment Score Plot (GSEA) of the TCA cycle (NES = 2.8, p-value = 0.0). (g) GSEA of the alanine, aspartate, and glutamate metabolism (NES = 2.42, p-value = 0.0). GSEA was conducted using GSEA software from the Broad Institute ( http://software.broadinstitute.org/gsea/index.jsp ).

Article Snippet: Prostate cancer cell lines LNCaP (ATCC ® CRL-1740TM) and PC3 (ATCC ® CRL-7934TM) were cultured in RPMI 1640 medium and Dulbecco’s Modified Eagle Medium (Thermo Fisher Scientific), respectively, supplemented with 10% FBS and penicillin/streptomycin.

Techniques: Expressing, Software

(a) GOT1 knockdown in LNCaP and PC3 prostate cancer cell lines. (b) GOT1 knockdown significantly inhibits cell viability in PC3 and LNCaP cells. (c) Invasion and (d) anchorage-independent growth in prostate cancer cell lines upon GOT1 knockdown. (e) GOT1 knockdown significantly increases ROS production in PC3 and LNCaP cells. The data from three independent experiments were expressed as mean ± SD.

Journal: bioRxiv

Article Title: Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery

doi: 10.1101/599514

Figure Lengend Snippet: (a) GOT1 knockdown in LNCaP and PC3 prostate cancer cell lines. (b) GOT1 knockdown significantly inhibits cell viability in PC3 and LNCaP cells. (c) Invasion and (d) anchorage-independent growth in prostate cancer cell lines upon GOT1 knockdown. (e) GOT1 knockdown significantly increases ROS production in PC3 and LNCaP cells. The data from three independent experiments were expressed as mean ± SD.

Article Snippet: Prostate cancer cell lines LNCaP (ATCC ® CRL-1740TM) and PC3 (ATCC ® CRL-7934TM) were cultured in RPMI 1640 medium and Dulbecco’s Modified Eagle Medium (Thermo Fisher Scientific), respectively, supplemented with 10% FBS and penicillin/streptomycin.

Techniques: Knockdown